DRHC Dubai Gynecology Clinic

Histological types of Cervical Carcinoma - Dubai Gynecology Clinic

Various Types of cervical cancer has been established based on the type of cell causing the cancer, and various treatment plan will apply accordingly.

1-Squamous cell carcinoma:

Approximately 70-75% of cervical carcinomas are squamous cell (outside layer of cells), which have been classified according to the cell type as; large cell non-keratinizing, large cell keratinizing and small cell carcinomas.

Verrucous squamous carcinoma:

  • It is as a rare type associated to HPV 6.
  • It is slow growing. Locally invasive.
  • It is composed of well differentiated squamous cells with Frond-like papillae and little apparent stromal invasion.
Papillary squamous carcinoma:
  • It has highly dysplastic squamous cells forming papillary fronds with thin fibro vascular core.
  • The appearance may be warty and fungating.
  • It is derived from the glandular cells of the cervix.
  • It’s evidence has been rising especially in woman younger than 35 years of age.
  • It might be diagnosed in advanced stage as it grows within the endocervical canal and the ectocervix appears in normal.  

 Adeno Malignum:

Adeno Malignum or minimal deviation adenocarcinoma. It occurs mainly in the fifth and sixth decade of life and it is well differentiated. Diagnosis require conization.   

 Adenoid cystic carcinoma:

it is considered the most aggressive.

3-Adeno squamous carcinoma:
  • It is a mixture of malignant squamous and glandular cells.
4-Neuro endocrine carcinomas:
  • It should be distinguished from small cell squamous tumor.
  • It has high frequency of lymphovascular invasion, lymph node metastasis and recurrence.


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