Limbal Stem Cell Deficiency (LSCD) at Eye Clinic DRHC Dubai

Overview of Limbal Stem Cell Deficiency (LSCD)

Limbal Stem Cell Deficiency (LSCD) is a condition affecting the cornea, the transparent front part of the eye. The cornea's clarity and function rely on limbal stem cells located at the corneal periphery (the limbus). These cells are crucial for corneal regeneration and repair. When these cells are deficient or dysfunctional, it can lead to severe vision problems and discomfort.

Causes of LSCD

LSCD can result from various causes, including:

• Genetic Disorder: Conditions like aniridia or ectodermal dysplasia.
• Acquired Conditions: Chemical burns, physical trauma, or surgeries affecting the eye.
• Inflammatory Diseases: Chronic conditions like Stevens-Johnson syndrome or ocular cicatricial pemphigoid.
• Contact Lens Overuse: Prolonged use of contact lenses, especially when not properly managed.

Symptom of LSCD

Individuals with LSCD may experience:

• Chronic eye pain and discomfort
• Persistent redness and inflammation
• Blurred vision or vision loss
• Recurrent or non-healing corneal erosions
• Sensitivity to light (photophobia)

Diagnosis of LSCD

Diagnosing LSCD involves a comprehensive eye examination. Specialized tests and imaging techniques such as:

• Slit Lamp Examination: To evaluate the corneal surface.
• Fluorescein Staining: To detect epithelial defects.
• In Vivo Confocal Microscopy: To assess the limbal stem cells and corneal structures.
• Impression Cytology: To analyze cell samples from the cornea and conjunctiva.

Treatment Options for LSCD

Treatment for LSCD aims to restore the ocular surface, relieve symptoms, and improve vision. At DRHC Dubai, we offer state-of-the-art treatments tailored to the severity and cause of LSCD:

1. Medical Management
   • Lubricating Eye Drops: To alleviate dryness and discomfort.
   • Anti-inflammatory Medications: To reduce inflammation and promote healing.
   • Bandage Contact Lenses: To protect the cornea and promote epithelialization.
2. Surgical Treatments
   • Amniotic Membrane Transplantation: Uses amniotic membrane to promote healing and reduce inflammation.
   • Conjunctival Limbal Autograft (CLAU): Transplants healthy limbal tissue from the patient's own eye.
   • Living-Related Conjunctival Limbal Allograft (lr-CLAL): Transplants limbal tissue from a living relative.
   • Cultivated Limbal Epithelial Transplantation (CLET): Uses lab-grown limbal stem cells for transplantation.
   • Keratolimbal Allograft (KLAL): Transplants limbal tissue from a deceased donor.

Why Choose DRHC Dubai for LSCD Treatment?

At DRHC Dubai, we provide cutting-edge treatments for LSCD, combining expertise, technology, and personalized care. Our team of experienced ophthalmologists is dedicated to delivering the highest standards of eye care. With advanced diagnostic tools and treatment options, we strive to restore vision and improve the quality of life for our patients.

At Dr. Rami Hamed Center, our Ophthalmology department is dedicated to safeguarding your vision health through expert eye care Professionals, Renowned as one of the best eye care clinics in Dubai our Ophthalmology Specialists provide services for Cataract, Retina treatment with Laser and Refractive surgeries.